Analysis of Prompt Engineering for Drug Toxicity Prediction
Clinical trials in the UK can cost up to {\pounds}1.3 million, with approximately 90% drug failure rate.
Why am I seeing this Ranked on source trust — arXiv
It ranks mainly on source trust: arXiv is the most reliable outlet we track on this subject, and is the only one on the story so far.
It clears the bar without leading strongly on any one factor. A middling score is not a claim that the story is important — only that nothing about it is weak.
Link-outLink-out, because it scores 0.40, below the 0.50 bar for a write-up. Link-out means we point at the publisher and say nothing of our own.
| Factor | Weight | Score | Contribution | Where it came from |
|---|---|---|---|---|
| Corroboration | 0.35 | 0.39 | +0.135 34% | 1 independent org on the story. Tier-3 aggregators never corroborate — they can show something is circulating, never that it is true. |
| Source trustleads | 0.25 | 0.85 | +0.212 53% | arXiv is the highest-trust source on this story and is first-party — the organisation announcing its own news. Trust is taken from the best source, not averaged. |
| Pickup rate | 0.20 | 0.00 | +0.000 0% | One counted organisation, so there is no spread to measure — nothing has picked this up to set a rate. |
| Freshness | 0.20 | 0.25 | +0.050 13% | Halves every 10 hours from the newest item on the story. This is the only factor that rewards a story for nothing more than being recent. |
Corroboration counts distinct organisations, once each, and only from tiers 1 and 2. Freshness halves every 10 hours, so this ranking is a snapshot and will differ at the next build.
What happened
Clinical trials in the UK can cost up to {\pounds}1.3 million, with approximately 90% drug failure rate. Toxicity is a major contributing factor in drug failure. In recent years, the use of artificial intelligence has been increasingly explored to aid in the prediction of drug toxicity, with extensive use of large language models (LLMs). However, LLMs can show considerable variation when minor changes are made to prompts, which raises concerns about their sensitivity to prompt engineering. Prompt engineering is used to optimise a prompt given to an LLM to generate the desired output. This paper proposes a method to analyse prompt engineering for drug toxicity prediction.
How this story arrived
Ordered by when each source was first observed, which is what the velocity figure is computed from. Publishers backdate; observed order does not.
- 01 Arxivfirst-party first seen Analysis of Prompt Engineering for Drug Toxicity Prediction
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